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Drug Delivery devices   are specialized technology for control and targeted release of drug. Drugs are being long used to improve health and extend lives since ages. The practice of drug delivery has changes dramatically in the last few decades. With Drug Delivery devices, medication discovered using the most advanced molecular biology strategies and having unacceptable side effects dues to drug interaction with parts of the body that are not target of drugs can be avoided. Drug delivery systems control the rate at which a drug is released and the target in the body where it is released. Side effect limits our ability to treat many diseases like neurodegenerative diseases, cancer, and infectious diseases; it is possible now with drug delivery devices. Administration of drug locally rather than systemically is a way to reduce side effect and drug toxicity and obtain maximum treatment impact. Application of ointment locally and injection of steroid to avoid joint pain are the few older w